Education

B.S., Biological Engineering, 2012, University of Maine
M.S., Biomedical Engineering, 2014, Columbia University
Ph.D., Biomedical Engineering, 2018 (expected), Columbia University

Curriculum Vitae

Areas of Research Interest

Tissue engineering; regenerative medicine; fluorescence microscopy; real-time calcium imaging; cellular response to pathologic cues in osteoarthritis

Background

Eben has always been fascinated by the complexity of living systems and has sought to understand how they work from the organ level down to the molecular.  The coupling of these academic interests with a love for problem solving and the creativity of design led him to pursue a career in biomedical engineering, where he can apply these interests to the improvement of the span and quality of human life.  As an undergraduate in Biological Engineering at the University of Maine, Eben began working in the Cellular Mechanics Laboratory where he completed an Honors Thesis on the influence of physically and chemically patterned substrates on axonal development.  Eben then sought out graduate programs in tissue engineering, seeking to apply his experience with cell based research to engineering at the tissue level, and was accepted into the Cellular Engineering Laboratory at Columbia University in 2012.  In working towards his doctoral degree Eben has performed research on the functional tissue engineering of articular cartilage, and has more recently begun working with real-time calcium imaging to support these tissue-level efforts with a greater understanding of phenomenon at the cellular level in both healthy and diseased joints.

Eben grew up in a small town in coastal Maine, and spends as much of his free time as possible in the outdoors.  He enjoys hiking, biking, skiing, and playing soccer, as well as photography and singing/songwriting on his piano.

Selected Publications

1. Stefani RM, Halder SS, Estell EG, Lee AJ, Silverstein AM, Sobczak E, Chahine NO, Ateshian GA, Shah RP, Hung CT. A Functional Tissue Engineered Synovium Model to Study Osteoarthritis Progression and Treatment. Tissue Eng Part A. 2018 Sep 11. doi: 10.1089/ten.TEA.2018.0142. [Epub ahead of print] link

2. Estell EG, Murphy LA, Silverstein AM, Tan AR, Shah RP, Ateshian GA, Hung CT. "Fibroblast-Like Synoviocyte Mechanosensitivity to Fluid Shear is Modulated by Interleukin-1α." Journal Biomech. [Epub ahead of print], 2017.

3. Page K, White C, Estell EG. “Treatment of incoherent scattering in bulk and nanocrystalline neutron total scattering experiments.” Journal of Applied Crystallography, Volume 44, pg. 532-539. June 2011.

4. Wise Jr. JP, Wise S, Wise J, McKay J, Browne M, Joyce K, Braun M, Wise C, Duffy R, Estell EG, Brown J, Gianios C, Mason M, Shehata T, Hammond D, Thompson WD, Wise Sr. JP. “Altered Gravity Exacerbates Chromate-Induced Genotoxicity.” Gravitational and Space Biology Bulletin 23(2) August 2010.